A recent question triggered this, although I've seen many such cases in the past (as I'm sure have others). In all such cases the OP describes some steps that have been followed and also seemingly anomalous results. This naturally leads to a bout of head-scratching as people consider the situation and post comments and answers positing all sorts of possible reasons and solutions.
The real issue arises when the OP admits (sometimes sheepishly) in a comment or a question update/edit or a self-answer that a mistake was made after all while following standard procedure and when that was corrected things worked exactly as one would expect.
I) Should such questions be closed as being Too Localized, since:
It's doubtful others will make the exact same mistake.
This will prevent others from also wasting their time attempting to answer, because often the OP's comment with their admission gets hidden by default.
II) If the community agrees that such questions should be closed, besides VTCing is there any way to highlight the Too Localized aspect so people don't waste their time? Leaving a comment for others might irk the OP (people don't like others pointing out their mistakes), and of course there's every chance that comment will get hidden as well.
Edit: Now that Too Localized has been entirely removed (unfortunately IMO, with no perfect substitute), this answer (including the comment by Jeff Atwood) is of particular interest. Don't forget to join the discussion on MSO and/or upvote relevant answers that discuss things no longer addressed by the current reasons for closure.